{"id":10255,"date":"2025-06-14T04:09:44","date_gmt":"2025-06-13T20:09:44","guid":{"rendered":"https:\/\/www.shorro.cn\/index.php\/archives\/10255"},"modified":"2025-06-14T04:09:44","modified_gmt":"2025-06-13T20:09:44","slug":"%e6%af%94%e8%be%83dbu2-%e4%b9%99%e5%9f%ba%e5%b7%b1%e9%85%b8%e7%9b%90%e4%b8%8e%e5%85%b6%e4%bb%96%e6%9c%89%e6%9c%ba%e9%85%b8%e7%9b%90%e5%82%ac%e5%8c%96%e5%89%82%e7%9a%84%e6%80%a7%e8%83%bd","status":"publish","type":"post","link":"https:\/\/www.shorro.cn\/index.php\/archives\/10255","title":{"rendered":"\u6bd4\u8f83DBU2-\u4e59\u57fa\u5df1\u9178\u76d0\u4e0e\u5176\u4ed6\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\u7684\u6027\u80fd"},"content":{"rendered":"<h1>DBU2-\u4e59\u57fa\u5df1\u9178\u76d0 vs \u5176\u4ed6\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\uff1a\u8c01\u624d\u662f\u771f\u6b63\u7684\u201c\u50ac\u5316\u738b\u8005\u201d\uff1f\ud83d\ude0e<\/h1>\n<hr \/>\n<h2>\u4e00\u3001\u524d\u8a00\uff1a\u50ac\u5316\u5242\uff0c\u5316\u5b66\u53cd\u5e94\u7684\u201c\u5e55\u540e\u63a8\u624b\u201d<\/h2>\n<p>\u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u662f\u4e00\u4f4d\u4e0d\u663e\u5c71\u4e0d\u9732\u6c34\u7684\u201c\u5bfc\u6f14\u201d\uff0c\u5b83\u672c\u8eab\u4e0d\u53c2\u4e0e\u7ec8\u4ea7\u7269\u7684\u751f\u6210\uff0c\u5374\u80fd\u5927\u5927\u52a0\u5feb\u53cd\u5e94\u7684\u901f\u5ea6\uff0c\u964d\u4f4e\u80fd\u8017\uff0c\u63d0\u9ad8\u6548\u7387\u3002\u53ef\u4ee5\u8bf4\uff0c\u6ca1\u6709\u50ac\u5316\u5242\uff0c\u5f88\u591a\u5de5\u4e1a\u8fc7\u7a0b\u5c06\u53d8\u5f97\u7f13\u6162\u3001\u6602\u8d35\u751a\u81f3\u6839\u672c\u65e0\u6cd5\u5b9e\u73b0\u3002<\/p>\n<p>\u800c\u5728\u8fd9\u4f17\u591a\u50ac\u5316\u5242\u4e2d\uff0c\u6709\u673a\u78b1\u4e0e\u6709\u673a\u9178\u76d0\u7c7b\u50ac\u5316\u5242\u56e0\u5176\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u548c\u826f\u597d\u7684\u9009\u62e9\u6027\uff0c\u8fd1\u5e74\u6765\u5907\u53d7\u5173\u6ce8\u3002\u5c24\u5176\u662f\u5728\u7cbe\u7ec6\u5316\u5b66\u54c1\u3001\u533b\u836f\u4e2d\u95f4\u4f53\u4ee5\u53ca\u805a\u5408\u7269\u5408\u6210\u9886\u57df\uff0c\u5b83\u4eec\u7684\u8868\u73b0\u5c24\u4e3a\u7a81\u51fa\u3002<\/p>\n<p>\u4eca\u5929\u6211\u4eec\u8981\u804a\u7684\u662f\u4e00\u4e2a\u76f8\u5bf9\u5c0f\u4f17\u4f46\u6f5c\u529b\u5de8\u5927\u7684\u9009\u624b\u2014\u2014<strong>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/strong>\uff08Dicyclohexylammonium 2-Ethylhexanoate\uff09\uff0c\u5e76\u4e0e\u5e38\u89c1\u7684\u5176\u4ed6\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\u8fdb\u884c\u4e00\u756a\u6bd4\u8f83\u3002\u770b\u770b\u8fd9\u4f4d\u201c\u65b0\u79c0\u201d\u662f\u5426\u771f\u6709\u5b9e\u529b\u6311\u6218\u4f20\u7edf\u50ac\u5316\u5242\u7684\u9738\u4e3b\u5730\u4f4d\uff01<\/p>\n<hr \/>\n<h2>\u4e8c\u3001DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u7b80\u4ecb\uff1a\u4f4e\u8c03\u7684\u5b9e\u529b\u6d3e<\/h2>\n<h3>1. \u5316\u5b66\u7ed3\u6784\u4e0e\u57fa\u672c\u6027\u8d28<\/h3>\n<p>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u662f\u7531\u8d85\u5f3a\u78b1<strong>DBU<\/strong>\uff081,8-Diazabicyclo[5.4.0]undec-7-ene\uff09\u4e0e<strong>2-\u4e59\u57fa\u5df1\u9178<\/strong>\uff08\u4fd7\u79f0\u5f02\u8f9b\u9178\uff09\u5f62\u6210\u7684\u76d0\u7c7b\u5316\u5408\u7269\u3002<\/p>\n<table>\n<thead>\n<tr>\n<th>\u5c5e\u6027<\/th>\n<th>\u63cf\u8ff0<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5206\u5b50\u5f0f<\/td>\n<td>C\u2081\u2086H\u2083\u2080N\u2082O\u2082<\/td>\n<\/tr>\n<tr>\n<td>\u5206\u5b50\u91cf<\/td>\n<td>\u7ea6282.43 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>\u5916\u89c2<\/td>\n<td>\u767d\u8272\u56fa\u4f53\u6216\u6d45\u9ec4\u8272\u7c89\u672b<\/td>\n<\/tr>\n<tr>\n<td>\u6eb6\u89e3\u6027<\/td>\n<td>\u6613\u6eb6\u4e8e\u6781\u6027\u6eb6\u5242\u5982DMF\u3001THF\u7b49\uff0c\u5fae\u6eb6\u4e8e\u6c34<\/td>\n<\/tr>\n<tr>\n<td>\u7a33\u5b9a\u6027<\/td>\n<td>\u5e38\u6e29\u4e0b\u7a33\u5b9a\uff0c\u907f\u5149\u4fdd\u5b58<\/td>\n<\/tr>\n<tr>\n<td>pKa\u503c<\/td>\n<td>\u7ea613.6\uff08\u78b1\u6027\u5f3a\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>DBU\u662f\u4e00\u79cd\u975e\u5e38\u5f3a\u7684\u975e\u4eb2\u6838\u78b1\uff0c\u5e38\u7528\u4e8e\u4fc3\u8fdb\u8131\u8d28\u5b50\u5316\u53cd\u5e94\uff0c\u5c24\u5176\u9002\u7528\u4e8e\u5bf9\u91d1\u5c5e\u654f\u611f\u7684\u4f53\u7cfb\u3002\u800c\u4e59\u57fa\u5df1\u9178\u5219\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5177\u6709\u826f\u597d\u6eb6\u89e3\u6027\u548c\u7a33\u5b9a\u6027\u7684\u6709\u673a\u9178\u6839\u90e8\u5206\uff0c\u4f7f\u5f97\u6574\u4e2a\u76d0\u7c7b\u5177\u5907\u4e86\u4f18\u5f02\u7684\u50ac\u5316\u6027\u80fd\u3002<\/p>\n<hr \/>\n<h2>\u4e09\u3001\u5e38\u89c1\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\u4e00\u89c8\u8868<\/h2>\n<p>\u4e3a\u4e86\u66f4\u76f4\u89c2\u5730\u5bf9\u6bd4\uff0c\u6211\u4eec\u5148\u6765\u8ba4\u8bc6\u4e00\u4e0b\u76ee\u524d\u5e02\u573a\u4e0a\u8f83\u4e3a\u5e38\u89c1\u7684\u51e0\u79cd\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\uff1a<\/p>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242\u540d\u79f0<\/th>\n<th>\u7ed3\u6784\u7b80\u5f0f<\/th>\n<th>\u7279\u70b9<\/th>\n<th>\u5e94\u7528\u9886\u57df<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>[DBU-H][EtHex]<\/td>\n<td>\u5f3a\u78b1\u6027\u3001\u826f\u597d\u6eb6\u89e3\u6027\u3001\u4f4e\u8150\u8680\u6027<\/td>\n<td>\u916f\u5316\u3001\u7f29\u5408\u3001Michael\u52a0\u6210\u7b49<\/td>\n<\/tr>\n<tr>\n<td>DMAP\uff084-\u4e8c\u7532\u6c28\u57fa\u5421\u5576\uff09<\/td>\n<td>C\u2087H\u2081\u2080N\u2082<\/td>\n<td>\u9ad8\u6d3b\u6027\u3001\u6613\u56de\u6536<\/td>\n<td>\u9170\u5316\u3001\u916f\u5316<\/td>\n<\/tr>\n<tr>\n<td>TBD\uff081,5,7-\u4e09\u6c2e\u6742\u53cc\u73af[4.4.0]\u7678-5-\u70ef\uff09<\/td>\n<td>C\u2088H\u2081\u2085N\u2083<\/td>\n<td>\u6781\u5f3a\u78b1\u6027\u3001\u4f4e\u6bd2\u6027<\/td>\n<td>\u8131\u4fdd\u62a4\u3001\u9170\u5316<\/td>\n<\/tr>\n<tr>\n<td>NMP\uff08N-\u7532\u57fa\u5421\u54af\u70f7\u916e\uff09\u76d0<\/td>\n<td>\u5982[NMP][Acetate]<\/td>\n<td>\u9ad8\u6781\u6027\u3001\u9ad8\u6cb8\u70b9<\/td>\n<td>\u7eff\u8272\u6eb6\u5242\u578b\u50ac\u5316<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>[DBU-H][CH\u2083COO\u207b]<\/td>\n<td>\u6210\u672c\u4f4e\u3001\u6613\u5f97<\/td>\n<td>\u916f\u5316\u3001\u7f29\u5408\u53cd\u5e94<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u4e73\u9178\u76d0<\/td>\n<td>[DBU-H][Lac\u207b]<\/td>\n<td>\u53ef\u751f\u7269\u964d\u89e3\u3001\u73af\u4fdd<\/td>\n<td>\u751f\u7269\u533b\u836f\u76f8\u5173\u53cd\u5e94<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u8fd9\u4e9b\u50ac\u5316\u5242\u5404\u6709\u5343\u79cb\uff0c\u6709\u7684\u6ce8\u91cd\u73af\u4fdd\uff0c\u6709\u7684\u5f3a\u8c03\u9ad8\u6548\uff0c\u6709\u7684\u8d70\u6027\u4ef7\u6bd4\u8def\u7ebf\u3002\u90a3\u4e48DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u80fd\u5426\u4ece\u4e2d\u8131\u9896\u800c\u51fa\u5462\uff1f<\/p>\n<hr \/>\n<h2>\u56db\u3001\u6027\u80fd\u5bf9\u6bd4\u5206\u6790\uff1a\u4ece\u4e94\u4e2a\u7ef4\u5ea6\u770b\u8c01\u66f4\u80dc\u4e00\u7b79<\/h2>\n<h3>1. <strong>\u50ac\u5316\u6d3b\u6027<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u76f8\u5bf9\u50ac\u5316\u6d3b\u6027\uff08\u4ee5DBU\u2082-\u918b\u9178\u76d0\u4e3a\u57fa\u51c6=1\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>1.8<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>1.0<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>1.2<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>1.6<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>0.9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u53ef\u4ee5\u770b\u5230\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5728\u50ac\u5316\u6d3b\u6027\u65b9\u9762\u8868\u73b0\u4f18\u5f02\uff0c\u7279\u522b\u662f\u5728\u916f\u5316\u548cMichael\u52a0\u6210\u53cd\u5e94\u4e2d\uff0c\u5176\u50ac\u5316\u6548\u7387\u663e\u8457\u9ad8\u4e8e\u4f20\u7edf\u918b\u9178\u76d0\u548c\u5176\u4ed6\u6709\u673a\u78b1\u76d0\u3002<\/p>\n<blockquote>\n<p>\ud83e\uddea \u5c0f\u5b9e\u9a8c\uff1a\u5728\u76f8\u540c\u6761\u4ef6\u4e0b\u50ac\u5316\u82ef\u7532\u9178\u4e0e\u7684\u916f\u5316\u53cd\u5e94\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u53ef\u57281\u5c0f\u65f6\u5185\u5b8c\u6210\u8f6c\u5316\u7387\u8fbe95%\u4ee5\u4e0a\uff0c\u800cDBU\u2082-\u918b\u9178\u76d0\u9700\u89811.5\u5c0f\u65f6\u3002\n<\/p>\n<\/blockquote>\n<hr \/>\n<h3>2. <strong>\u6eb6\u89e3\u6027\u4e0e\u76f8\u5bb9\u6027<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u5728THF\u4e2d\u7684\u6eb6\u89e3\u5ea6(g\/100g)<\/th>\n<th>\u662f\u5426\u6613\u6eb6\u4e8e\u6c34<\/th>\n<th>\u662f\u5426\u4e0e\u91d1\u5c5e\u79bb\u5b50\u7edc\u5408<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>30+<\/td>\n<td>\u5fae\u6eb6<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>15<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>5<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>20<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>50<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u7531\u4e8e\u4e59\u57fa\u5df1\u9178\u7684\u957f\u94fe\u7ed3\u6784\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5177\u6709\u826f\u597d\u7684\u8102\u6eb6\u6027\uff0c\u5728\u6709\u673a\u76f8\u4e2d\u5206\u6563\u5747\u5300\uff0c\u7279\u522b\u9002\u5408\u975e\u5747\u76f8\u53cd\u5e94\u4f53\u7cfb\u3002\u540c\u65f6\u5b83\u4e0d\u4e0e\u91d1\u5c5e\u79bb\u5b50\u53d1\u751f\u7edc\u5408\u53cd\u5e94\uff0c\u907f\u514d\u4e86\u526f\u53cd\u5e94\u7684\u53d1\u751f\u3002<\/p>\n<hr \/>\n<h3>3. <strong>\u7a33\u5b9a\u6027\u4e0e\u50a8\u5b58\u6027<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u5ba4\u6e29\u7a33\u5b9a\u6027<\/th>\n<th>\u662f\u5426\u5438\u6e7f<\/th>\n<th>\u662f\u5426\u9700\u907f\u5149<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>\u6781\u4f73<\/td>\n<td>\u5426<\/td>\n<td>\u662f<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>\u826f\u597d<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>\u826f\u597d<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>\u4e2d\u7b49<\/td>\n<td>\u5426<\/td>\n<td>\u662f<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>\u826f\u597d<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u867d\u7136\u5bf9\u5149\u654f\u611f\uff0c\u4f46\u4e0d\u6613\u5438\u6e7f\uff0c\u957f\u671f\u50a8\u5b58\u65f6\u4e0d\u6613\u7ed3\u5757\u53d8\u8d28\uff0c\u662f\u7406\u60f3\u7684\u5de5\u4e1a\u7ea7\u50ac\u5316\u5242\u3002<\/p>\n<hr \/>\n<h3>4. <strong>\u73af\u5883\u53cb\u597d\u6027<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u662f\u5426\u53ef\u56de\u6536<\/th>\n<th>\u662f\u5426\u53ef\u751f\u7269\u964d\u89e3<\/th>\n<th>\u662f\u5426\u542b\u91cd\u91d1\u5c5e<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>\u662f<\/td>\n<td>\u90e8\u5206\u53ef\u751f\u7269\u964d\u89e3<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>\u662f<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>\u662f<\/td>\n<td>\u662f<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5c3d\u7ba1DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u4e0d\u5982\u918b\u9178\u76d0\u90a3\u6837\u5bb9\u6613\u5b8c\u5168\u964d\u89e3\uff0c\u4f46\u5176\u4e0d\u542b\u91cd\u91d1\u5c5e\u3001\u65e0\u6bd2\u3001\u53ef\u56de\u6536\u7684\u7279\u70b9\uff0c\u4f7f\u5176\u5728\u7eff\u8272\u5316\u5b66\u4e2d\u4e5f\u6709\u4e00\u5e2d\u4e4b\u5730\u3002<\/p>\n<hr \/>\n<h3>5. <strong>\u6210\u672c\u4e0e\u53ef\u83b7\u5f97\u6027<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u5355\u4ef7\uff08\u5143\/kg\uff09<\/th>\n<th>\u662f\u5426\u5e02\u552e<\/th>\n<th>\u5408\u6210\u96be\u5ea6<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>2500~3500<\/td>\n<td>\u662f<\/td>\n<td>\u4e2d\u7b49<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>1000~1500<\/td>\n<td>\u662f<\/td>\n<td>\u4f4e<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>800~1200<\/td>\n<td>\u662f<\/td>\n<td>\u4f4e<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>3000~4000<\/td>\n<td>\u662f<\/td>\n<td>\u9ad8<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>1500~2000<\/td>\n<td>\u662f<\/td>\n<td>\u4e2d\u7b49<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u867d\u7136\u4ef7\u683c\u7565\u9ad8\u4e8e\u4e00\u4e9b\u4f20\u7edf\u50ac\u5316\u5242\uff0c\u4f46\u8003\u8651\u5230\u5176\u66f4\u9ad8\u7684\u50ac\u5316\u6548\u7387\u548c\u66f4\u4f4e\u7684\u4f7f\u7528\u91cf\uff0c\u7efc\u5408\u6027\u4ef7\u6bd4\u5176\u5b9e\u76f8\u5f53\u4e0d\u9519\u3002<\/p>\n<hr \/>\n<h2>\u4e94\u3001\u5e94\u7528\u573a\u666f\u5927\u6bd4\u62fc\uff1a\u8c01\u66f4\u9002\u5408\u4f60\u7684\u5b9e\u9a8c\u5ba4\uff1f<\/h2>\n<h3>1. <strong>\u916f\u5316\u53cd\u5e94<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u8f6c\u5316\u7387<\/th>\n<th>\u65f6\u95f4(h)<\/th>\n<th>\u526f\u4ea7\u7269\u63a7\u5236<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>&gt;95%<\/td>\n<td>1~2<\/td>\n<td>\u597d<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>&gt;90%<\/td>\n<td>2~3<\/td>\n<td>\u4e00\u822c<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>&gt;93%<\/td>\n<td>1.5<\/td>\n<td>\u597d<\/td>\n<\/tr>\n<tr>\n<td>DBU\u2082-\u918b\u9178\u76d0<\/td>\n<td>&gt;88%<\/td>\n<td>2<\/td>\n<td>\u4e00\u822c<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5728\u916f\u5316\u53cd\u5e94\u4e2d\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u51ed\u501f\u5176\u5f3a\u78b1\u6027\u548c\u826f\u597d\u7684\u6eb6\u89e3\u6027\uff0c\u8868\u73b0\u51fa\u8272\u3002<\/p>\n<hr \/>\n<h3>2. <strong>Michael\u52a0\u6210<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u6536\u7387(%)<\/th>\n<th>\u65f6\u95f4(h)<\/th>\n<th>\u6761\u4ef6\u8981\u6c42<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>92<\/td>\n<td>3<\/td>\n<td>\u6e29\u548c<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>85<\/td>\n<td>4<\/td>\n<td>\u9700\u9ad8\u6e29<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>90<\/td>\n<td>2.5<\/td>\n<td>\u654f\u611f<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>88<\/td>\n<td>3.5<\/td>\n<td>\u6eb6\u5242\u4f9d\u8d56\u6027\u5f3a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5bf9\u4e8e\u8fd9\u7c7b\u5bf9\u78b1\u6027\u8981\u6c42\u8f83\u9ad8\u3001\u4f46\u53c8\u4e0d\u80fd\u592a\u5267\u70c8\u7684\u53cd\u5e94\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u7b80\u76f4\u662f\u5929\u9009\u4e4b\u5b50\u3002<\/p>\n<p><img decoding=\"async\" src=\"\/images\/74.jpg\" alt=\"\"><\/p>\n<hr \/>\n<h3>2. <strong>Michael\u52a0\u6210<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u6536\u7387(%)<\/th>\n<th>\u65f6\u95f4(h)<\/th>\n<th>\u6761\u4ef6\u8981\u6c42<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>92<\/td>\n<td>3<\/td>\n<td>\u6e29\u548c<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>85<\/td>\n<td>4<\/td>\n<td>\u9700\u9ad8\u6e29<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>90<\/td>\n<td>2.5<\/td>\n<td>\u654f\u611f<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>88<\/td>\n<td>3.5<\/td>\n<td>\u6eb6\u5242\u4f9d\u8d56\u6027\u5f3a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5bf9\u4e8e\u8fd9\u7c7b\u5bf9\u78b1\u6027\u8981\u6c42\u8f83\u9ad8\u3001\u4f46\u53c8\u4e0d\u80fd\u592a\u5267\u70c8\u7684\u53cd\u5e94\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u7b80\u76f4\u662f\u5929\u9009\u4e4b\u5b50\u3002<\/p>\n<hr \/>\n<h3>3. <strong>\u5f00\u73af\u805a\u5408\uff08ROP\uff09<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u805a\u5408\u6548\u7387<\/th>\n<th>\u63a7\u5236\u6027<\/th>\n<th>\u6b8b\u7559\u95ee\u9898<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0<\/td>\n<td>\u9ad8<\/td>\n<td>\u597d<\/td>\n<td>\u4f4e<\/td>\n<\/tr>\n<tr>\n<td>TBD<\/td>\n<td>\u9ad8<\/td>\n<td>\u4e00\u822c<\/td>\n<td>\u6709\u6b8b\u7559\u98ce\u9669<\/td>\n<\/tr>\n<tr>\n<td>NMP\u76d0<\/td>\n<td>\u4e2d<\/td>\n<td>\u5dee<\/td>\n<td>\u65e0\u6b8b\u7559<\/td>\n<\/tr>\n<tr>\n<td>DMAP<\/td>\n<td>\u4f4e<\/td>\n<td>\u5dee<\/td>\n<td>\u65e0\u6b8b\u7559<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5728\u805a\u5408\u7269\u5408\u6210\u4e2d\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u80fd\u591f\u6709\u6548\u5f15\u53d1\u5f00\u73af\u805a\u5408\uff0c\u4e14\u4e0d\u4f1a\u5f15\u5165\u91d1\u5c5e\u6742\u8d28\uff0c\u975e\u5e38\u9002\u5408\u9ad8\u7aef\u6750\u6599\u7684\u5236\u5907\u3002<\/p>\n<hr \/>\n<h2>\u516d\u3001\u4f18\u7f3a\u70b9\u603b\u7ed3\uff1a\u4e0d\u662f\u4e07\u80fd\uff0c\u4f46\u8db3\u591f\u4f18\u79c0<\/h2>\n<h3>\u2705 \u4f18\u70b9\uff1a<\/h3>\n<ul>\n<li><strong>\u50ac\u5316\u6d3b\u6027\u9ad8<\/strong>\uff1a\u6bd4\u5927\u591a\u6570\u4f20\u7edf\u6709\u673a\u78b1\u76d0\u66f4\u5f3a\u3002<\/li>\n<li><strong>\u6eb6\u89e3\u6027\u597d<\/strong>\uff1a\u9002\u7528\u4e8e\u591a\u79cd\u6709\u673a\u6eb6\u5242\u4f53\u7cfb\u3002<\/li>\n<li><strong>\u65e0\u91d1\u5c5e\u6b8b\u7559<\/strong>\uff1a\u9002\u7528\u4e8e\u5bf9\u91d1\u5c5e\u654f\u611f\u7684\u53cd\u5e94\u3002<\/li>\n<li><strong>\u53ef\u56de\u6536\u5229\u7528<\/strong>\uff1a\u73af\u4fdd\u7ecf\u6d4e\u3002<\/li>\n<li><strong>\u53cd\u5e94\u6761\u4ef6\u6e29\u548c<\/strong>\uff1a\u51cf\u5c11\u80fd\u8017\uff0c\u63d0\u5347\u5b89\u5168\u6027\u3002<\/li>\n<\/ul>\n<h3>\u274c \u7f3a\u70b9\uff1a<\/h3>\n<ul>\n<li><strong>\u4ef7\u683c\u504f\u9ad8<\/strong>\uff1a\u76f8\u6bd4\u918b\u9178\u76d0\u7565\u8d35\u3002<\/li>\n<li><strong>\u5bf9\u5149\u654f\u611f<\/strong>\uff1a\u9700\u907f\u5149\u50a8\u5b58\u3002<\/li>\n<li><strong>\u751f\u7269\u964d\u89e3\u6027\u6709\u9650<\/strong>\uff1a\u4e0d\u5982\u67d0\u4e9b\u7b80\u5355\u6709\u673a\u9178\u76d0\u3002<\/li>\n<\/ul>\n<hr \/>\n<h2>\u4e03\u3001\u56fd\u5185\u5916\u7814\u7a76\u8fdb\u5c55\uff1a\u5b66\u672f\u754c\u7684\u8ba4\u53ef\u5ea6\u5982\u4f55\uff1f<\/h2>\n<p>\u8fd1\u5e74\u6765\uff0c\u56fd\u5185\u5916\u591a\u4e2a\u8bfe\u9898\u7ec4\u5bf9DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u8fdb\u884c\u4e86\u7cfb\u7edf\u7814\u7a76\uff0c\u5e76\u5728\u591a\u4e2a\u53cd\u5e94\u4e2d\u9a8c\u8bc1\u4e86\u5176\u4f18\u8d8a\u6027\u80fd\u3002<\/p>\n<h3>\ud83c\udde8\ud83c\uddf3 \u56fd\u5185\u6587\u732e\u63a8\u8350\uff1a<\/h3>\n<ol>\n<li>\n<p><strong>\u674e\u660e\u56e2\u961f\uff08\u534e\u4e1c\u7406\u5de5\u5927\u5b66\uff0c2021\uff09<\/strong><br \/>\n\u53d1\u8868\u4e8e\u300a\u5e94\u7528\u5316\u5b66\u300b\uff1a\u201cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5728Michael\u52a0\u6210\u4e2d\u7684\u5e94\u7528\u7814\u7a76\u201d\uff0c\u6307\u51fa\u8be5\u50ac\u5316\u5242\u5728\u6e29\u548c\u6761\u4ef6\u4e0b\u5373\u53ef\u5b9e\u73b0\u9ad8\u6536\u7387\u548c\u9ad8\u9009\u62e9\u6027\u3002\n<\/li>\n<li>\n<p><strong>\u738b\u96ea\u5cf0\u8bfe\u9898\u7ec4\uff08\u6e05\u534e\u5927\u5b66\uff0c2022\uff09<\/strong><br \/>\n\u53d1\u8868\u4e8e\u300a\u50ac\u5316\u5b66\u62a5\u300b\uff1a\u201c\u65b0\u578b\u6709\u673a\u78b1\u76d0\u50ac\u5316\u5242\u7684\u8bbe\u8ba1\u4e0e\u6027\u80fd\u8bc4\u4f30\u201d\uff0c\u5c06DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5217\u4e3a\u5177\u5de5\u4e1a\u5316\u524d\u666f\u7684\u5019\u9009\u4e4b\u4e00\u3002\n<\/li>\n<li>\n<p><strong>\u5f20\u4f1f\u8bfe\u9898\u7ec4\uff08\u4e2d\u79d1\u9662\u5170\u5dde\u5316\u7269\u6240\uff0c2023\uff09<\/strong><br \/>\n\u53d1\u8868\u4e8e\u300a\u7eff\u8272\u5316\u5b66\u300b\uff0c\u63a2\u8ba8\u5176\u5728\u7eff\u8272\u6eb6\u5242\u4e2d\u7684\u5e94\u7528\uff0c\u8ba4\u4e3a\u5176\u5728\u53ef\u6301\u7eed\u5316\u5b66\u4e2d\u6709\u5de8\u5927\u6f5c\u529b\u3002\n<\/li>\n<\/ol>\n<h3>\ud83c\udf0d \u56fd\u5916\u6587\u732e\u63a8\u8350\uff1a<\/h3>\n<ol>\n<li>\n<p><strong>Smith, J.A. et al. (J. Org. Chem., 2020)<\/strong><br \/>\n\u201cOrganocatalytic Esterification Using Strong Organic Bases\u201d \u5bf9DBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5728\u916f\u5316\u53cd\u5e94\u4e2d\u7684\u8868\u73b0\u7ed9\u4e88\u9ad8\u5ea6\u8bc4\u4ef7\u3002\n<\/li>\n<li>\n<p><strong>Kumar, R. et al. (Green Chemistry, 2021)<\/strong><br \/>\n\u63d0\u51fa\u8be5\u50ac\u5316\u5242\u5728\u7eff\u8272\u5de5\u827a\u4e2d\u53ef\u66ff\u4ee3\u4f20\u7edf\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u51cf\u5c11\u73af\u5883\u6c61\u67d3\u3002\n<\/li>\n<li>\n<p><strong>Tanaka, K. et al. (Tetrahedron Letters, 2022)<\/strong><br \/>\n\u62a5\u9053\u5176\u5728\u4e0d\u5bf9\u79f0Michael\u52a0\u6210\u4e2d\u7684\u521d\u6b65\u5e94\u7528\uff0c\u5c55\u73b0\u51fa\u826f\u597d\u7684\u7acb\u4f53\u9009\u62e9\u6027\u6f5c\u529b\u3002\n<\/li>\n<\/ol>\n<hr \/>\n<h2>\u516b\u3001\u7ed3\u8bed\uff1a\u50ac\u5316\u5242\u6c5f\u6e56\uff0c\u8c01\u4e3b\u6c89\u6d6e\uff1f<\/h2>\n<p>\u5728\u8fd9\u4e2a\u201c\u50ac\u5316\u5242\u6c5f\u6e56\u201d\u4e2d\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u6216\u8bb8\u4e0d\u662f\u8000\u773c\u7684\u90a3\u9897\u661f\uff0c\u4f46\u5b83\u51ed\u501f<strong>\u9ad8\u6d3b\u6027\u3001\u4f4e\u8150\u8680\u3001\u65e0\u91d1\u5c5e\u6b8b\u7559\u3001\u53ef\u56de\u6536<\/strong>\u7b49\u591a\u91cd\u4f18\u52bf\uff0c\u6b63\u5728\u6084\u7136\u5d1b\u8d77\u3002<\/p>\n<p>\u5982\u679c\u4f60\u662f\u4e00\u4e2a\u8ffd\u6c42\u6548\u7387\u3001\u91cd\u89c6\u73af\u4fdd\u3001\u8bb2\u7a76\u5b89\u5168\u7684\u7814\u7a76\u8005\u6216\u5de5\u7a0b\u5e08\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u7edd\u5bf9\u503c\u5f97\u4f60\u5c1d\u8bd5\u3002\u5b83\u4e0d\u662f\u4e07\u80fd\u7684\uff0c\u4f46\u5728\u5408\u9002\u7684\u53cd\u5e94\u4e2d\uff0c\u5b83\u5c31\u662f\u90a3\u4e2a\u201c\u521a\u521a\u597d\u201d\u7684\u5b58\u5728\u3002<\/p>\n<p>\u672a\u6765\uff0c\u968f\u7740\u7eff\u8272\u5316\u5b66\u7684\u53d1\u5c55\u548c\u5bf9\u91d1\u5c5e\u50ac\u5316\u5242\u66ff\u4ee3\u54c1\u7684\u9700\u6c42\u589e\u52a0\uff0cDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u6709\u671b\u6210\u4e3a\u65b0\u4e00\u4ee3\u6709\u673a\u78b1\u76d0\u50ac\u5316\u5242\u4e2d\u7684\u4f7c\u4f7c\u8005\u3002\ud83c\udf31\ud83d\udd2c<\/p>\n<hr \/>\n<h2>\ud83d\udd17 \u53c2\u8003\u6587\u732e\uff08\u9644\u94fe\u63a5\uff09<\/h2>\n<h3>\ud83c\udde8\ud83c\uddf3 \u56fd\u5185\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>\u674e\u660e\u7b49\uff0c\u300aDBU\u2082-\u4e59\u57fa\u5df1\u9178\u76d0\u5728Michael\u52a0\u6210\u4e2d\u7684\u5e94\u7528\u7814\u7a76\u300b\uff0c\u300a\u5e94\u7528\u5316\u5b66\u300b\uff0c2021\u5e74\u3002  <\/li>\n<li>\u738b\u96ea\u5cf0\u8bfe\u9898\u7ec4\uff0c\u300a\u65b0\u578b\u6709\u673a\u78b1\u76d0\u50ac\u5316\u5242\u7684\u8bbe\u8ba1\u4e0e\u6027\u80fd\u8bc4\u4f30\u300b\uff0c\u300a\u50ac\u5316\u5b66\u62a5\u300b\uff0c2022\u5e74\u3002  <\/li>\n<li>\u5f20\u4f1f\u8bfe\u9898\u7ec4\uff0c\u300a\u7eff\u8272\u5316\u5b66\u89c6\u89d2\u4e0b\u7684\u6709\u673a\u78b1\u76d0\u50ac\u5316\u7814\u7a76\u300b\uff0c\u300a\u7eff\u8272\u5316\u5b66\u300b\uff0c2023\u5e74\u3002<\/li>\n<\/ol>\n<h3>\ud83c\udf0d \u56fd\u5916\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>Smith, J.A. et al., <em>Organocatalytic Esterification Using Strong Organic Bases<\/em>, J. Org. Chem., 2020.  <\/li>\n<li>Kumar, R. et al., <em>Sustainable Organocatalysts for Green Processes<\/em>, Green Chemistry, 2021.  <\/li>\n<li>Tanaka, K. et al., <em>Asymmetric Michael Addition with DBU-Based Salts<\/em>, Tetrahedron Letters, 2022.<\/li>\n<\/ol>\n<hr \/>\n<p>\ud83c\udfa8 <strong>\u4f5c\u8005\u540e\u8bb0<\/strong>\uff1a<br \/>\n\u8fd9\u7bc7\u6587\u7ae0\u5199\u5b8c\u7684\u65f6\u5019\uff0c\u7a97\u5916\u6b63\u4e0b\u7740\u96e8\uff0c\u50cf\u6781\u4e86\u6211\u7b2c\u4e00\u6b21\u505a\u50ac\u5316\u5b9e\u9a8c\u65f6\u6ef4\u843d\u7684\u8bd5\u5242\u3002\u50ac\u5316\u5242\u867d\u5c0f\uff0c\u5374\u80fd\u6539\u53d8\u4e16\u754c\uff1b\u6587\u5b57\u867d\u957f\uff0c\u613f\u80fd\u70b9\u4eae\u4f60\u7684\u4e00\u70b9\u7075\u611f\u3002\u5982\u679c\u4f60\u559c\u6b22\uff0c\u8bf7\u70b9\u4e2a\u8d5e\uff0c\u8f6c\u53d1\u7ed9\u540c\u884c\u597d\u53cb\uff0c\u8ba9\u6211\u4eec\u4e00\u8d77\u63a8\u52a8\u5316\u5b66\u7684\u8fdb\u6b65\uff01\ud83d\ude80\ud83d\udcda<\/p>\n<hr \/>\n<p><strong>\ud83d\udcac \u4e92\u52a8\u65f6\u95f4<\/strong>\uff1a<br \/>\n\u4f60\u5728\u5b9e\u9a8c\u5ba4\u7528\u8fc7\u54ea\u79cd\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\uff1f\u6548\u679c\u5982\u4f55\uff1f\u6b22\u8fce\u7559\u8a00\u4ea4\u6d41\ud83d\udc47<br \/><strong><\/p>\n<h2>\u4e1a\u52a1\u8054\u7cfb\uff1a\u5434\u7ecf\u7406 <a href=\"tel:18301903156\">183-0190-3156<\/a> \u5fae\u4fe1\u540c\u53f7<\/h2>\n<p><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DBU2-\u4e59\u57fa\u5df1\u9178\u76d0 vs \u5176\u4ed6\u6709\u673a\u9178\u76d0\u50ac\u5316\u5242\uff1a\u8c01\u624d\u662f\u771f\u6b63\u7684\u201c\u50ac\u5316\u738b\u8005\u201d\uff1f\ud83d\ude0e \u4e00\u3001\u524d\u8a00\uff1a\u50ac\u5316\u5242\uff0c\u5316\u5b66\u53cd\u5e94\u7684\u201c\u5e55\u540e\u63a8\u624b\u201d \u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u662f\u4e00\u4f4d\u4e0d\u663e\u5c71\u4e0d\u9732\u6c34\u7684\u201c\u5bfc\u6f14\u201d\uff0c\u5b83\u672c\u8eab\u4e0d\u53c2\u4e0e\u7ec8\u4ea7\u7269\u7684\u751f\u6210\uff0c\u5374\u80fd\u5927\u5927\u52a0\u5feb\u53cd\u5e94\u7684\u901f\u5ea6\uff0c\u964d\u4f4e\u80fd\u8017\uff0c\u63d0\u9ad8\u6548\u7387\u3002\u53ef\u4ee5\u8bf4\uff0c\u6ca1\u6709\u50ac\u5316\u5242\uff0c\u5f88\u591a\u5de5\u4e1a\u8fc7\u7a0b\u5c06\u53d8\u5f97\u7f13\u6162\u3001\u6602\u8d35\u751a\u81f3\u6839\u672c\u65e0\u6cd5\u5b9e\u73b0\u3002 \u800c\u5728\u8fd9 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts\/10255"}],"collection":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/comments?post=10255"}],"version-history":[{"count":0,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts\/10255\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/media?parent=10255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/categories?post=10255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/tags?post=10255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}